Alkaloids
4 guides tagged Alkaloids
Explainer
Kanna Alkaloids: The Full Sceletium Profile, Explained
Kanna's effects come from a family of mesembrine-type alkaloids, not a single active. Here is the whole profile, what each one does, and why the ratio between them, not just the total content, is what really shapes a product's character.
Read the guide →~10 min
Explainer
Mesembrine: Kanna's Signature Alkaloid, Explained
Mesembrine is the principal alkaloid of Sceletium tortuosum and the most potent serotonin-reuptake inhibitor among kanna's compounds. Here is what it is, how it differs from mesembrenone, and why a disclosed mesembrine % is the number that tells you what you are actually buying.
Read the guide →~10 min
Explainer
Mesembrenone: Kanna's PDE4 Alkaloid, Explained
Mesembrenone is kanna's other principal alkaloid and the most potent PDE4 inhibitor among the plant's compounds (while also serotonin-transporter active). Here is what it is, how it differs from mesembrine, and why the standardized Zembrin extract is deliberately built around it.
Read the guide →~10 min
Buyer's Guide
The Best Kanna Tinctures, Reviewed (2026)
Fast sublingual onset and total dose-by-the-drop control, the kanna tinctures worth buying, ranked on alkaloid concentration, transparency, and cost per dose.
Read the guide →9 min